当前分类：首页 > 全部产品 > 实验试剂 > 细胞因子

重组人碱性成纤维细胞生长因子bFGF,bFGF Recombinant Human Protein

货号：13256029

品牌：Invitrogen

货期：2-3周

价格：￥2640

规格：

10ug

数量：

加入购物车立即购买

产品介绍
商品属性
资料下载
产品问答

产品规格

种属

Human

表达系统

E.coli

分类

Recombinant

类型

Protein

Purity

≥95% by SDS-PAGE

Endotoxin concentration

≤0.1 ng/µg

Activity

ED50 < 1.0 ng/mL; determined by the dose-dependent stimulation of BALB/3T3 cells.

偶联物

Unconjugated

形式

Lyophilized

纯化类型

SDS-PAGE

内含物

no preservative

保存条件

-20°C

产品详细信息

Carrier-Free

Reconstitution: Reconstitute in 100 µL of 10 mM Tris, pH 7.6, to yield a stock solution of 0.1 mg/mL of bFGF. To avoid loss due to adsorption, prepare dilute solutions in appropriate assay buffer containing at least 0.1% BSA just prior to use. Do not store in dilute solution. For longer term storage, aliquot into buffer containing 0.1% BSA and store in polypropylene vials at -20°C. Avoid repeated freezing and thawing. In applications requiring long-term use of this growth factor in cell cultures, refilter material after dilution in BSA-containing buffer, through a 0.22 micron low protein-binding filter Storage: Six months at -20°C as received. Up to six months at -20°C when aliquoted into solution containing carrier protein (see Reconstitution Recommendation). NOTE: Do not store in dilute aqueous solution. Avoid repeated freeze/thaw.

靶标信息

FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

品牌：	Gibco
规格：	10ug
储存温度：	-20℃
保质期：	两年
产品说明：	期货产品，下单后无法取消！

暂无信息

最新公告：

重组人碱性成纤维细胞生长因子bFGF,bFGF Recombinant Human Protein

产品详细信息

靶标信息

最新发布

PVDF免疫印迹膜 PVDF Western Blotting Membranes 0.2um 30cm*3M

针式过滤器,焊接式,PVDF/亲水聚偏氟乙烯,13mm*0.45um(进口膜)

透析袋(宽10MM/直径6MM/1000分子量)

Purer Al2O3-N 中性氧化铝固相萃取柱(SPE),100mg/1ml